(Attn.editors: The following press release comes to you under

first_imgan arrangement with PRNewswire. PTI takes no editorial responsibility for the same). Glenmarks Bi-Specific Antibody – GBR 1302 to Enter Phase I Trials MUMBAI, September 15, 2015/PRNewswire/ — – GBR 1302, a HER2xCD3 bi-specific antibody has successfully completed the preclinical evaluation phase – Preclinically, GBR 1302 has demonstrated superiority over current antibody therapies against most HER2 positive cancers, including breast cancer – The phase 1 trial application for this antibody has been submitted to German regulatory authorities. – GBR 1302 has the potential to be used in the treatment a broad array of cancers including breast cancer – If confirmed in clinical trials, GBR 1302 could constitute an innovative treatment for HER2 positive cancers, potentially superior to the currently available monoclonal antibody treatments Glenmark Pharmaceuticals S.A. (GPSA), a wholly-owned subsidiary of Glenmark Pharmaceuticals Limited India (GPL), announces the completion of Phase 1 supporting studies and the submission of a clinical trial application to the Paul-Ehrlich Institute in Germany with a novel clinical development candidate, GBR 1302. GBR 1302 is a HER2xCD3 bi-specific antibody based on Glenmarks proprietary BEAT(TM) platform. GBR 1302 is the first clinical development candidate based on the BEAT(TM) technology. Glenmark expects to obtain approval for the initiation of clinical studies with GBR1302 during this financial year. MORE PRNewswire GSVlast_img read more

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Administrations Global Health Cuts Could Lead To Catastrophic Loss Of Life

first_imgAdministration’s Global Health Cuts Could Lead To ‘Catastrophic Loss Of Life’ The White House proposes reducing funding to major programs including the President’s Emergency Plan for AIDS Relief, help for aid organizations that provide family planning and other health services and contributions to the United Nations Population Fund. Meanwhile, experts are “very concerned” that the Trump administration is not prepared to deal with a pandemic outbreak, and an idea that all research should serve a national purpose sparks debate. A musical called “The Great Immensity” made its New York premiere in 2014, the product of nearly $700,000 in grants from the National Science Foundation. Aimed at increasing awareness of the widespread impacts of climate change, the musical featured one song that explained the emergence of the global economy and another on the extinction of the passenger pigeon. It was widely panned. The production, however, made a brief comeback earlier this year — not on stage, but in an outline of the House Committee on Science, Space, and Technology’s authorization and oversight plan. According to the committee, grant awards like the ones used to fund the musical necessitated a crackdown: Lawmakers must ensure that all grants serve “the national interest.” (Facher, 4/10) This is part of the KHN Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription. Los Angeles Times: Trump Pushes Historic Cuts In Global Health Aid, Stoking Fears Of New Disease Outbreaks And Diminished U.S. Clout And in other news — The Washington Post: The Trump Administration Is Ill-Prepared For A Global Pandemic Half a century after the United States led a global expansion of international efforts to combat infectious disease and promote family planning, the Trump administration has embarked on a historic retrenchment that many fear threatens the health of millions and jeopardizes America’s standing in the world. Since taking office, President Trump has proposed dramatic cuts to the U.S. Agency for International Development, which has historically spearheaded U.S. efforts to improve women’s and children’s health. (Levey, 4/10) The Wall Street Journal: Impact Of Federal Hiring Freeze Seen At Veterans Affairs, Prisons, Social Security The Trump administration has failed to fill crucial public health positions across the government, leaving the nation ill-prepared to face one of its greatest potential threats: a pandemic outbreak of a deadly infectious disease, according to experts in health and national security. No one knows where or when the next outbreak will occur, but health security experts say it is inevitable. Every president since Ronald Reagan has faced threats from infectious diseases, and the number of outbreaks is on the rise. (Sun, 4/8) Stat: Push For Science In The ‘National Interest’ Puts Some On Edge The hiring freeze President Donald Trump ordered on his first full working day in the White House is threatening to compromise the safety of correctional officers, delay payments to veterans and prevent disabled and retired Americans from getting their Social Security checks on time, union officials and government workers say. (Reinhard and Ballhaus, 4/9) last_img read more

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